It is a type of multiple choice question. A Type R item consists of 1) theme, 2) lead-in, 3) option list, and 4) stems. The number of options allowed is from 4 to up to 26. While in a Type A item five options are used only for the item, Type R items use one list of options for all items in the set. Ex) Theme: fatigue For each item, select the suggested number of the most likely diagnosis among the 14 options. Acute leukemia Anemia of chronic disease Congestive heart failure Depression Epstein-Barr Virus Folic Acid Deficiency Glucose 6-phosphate dehydrogenase deficiency Hereditary spherocytosis Hypothyroidism Iron deficiency Lyme disease Microangiopathic Hemolytic Anemia Miliary tuberculosis Vitamin B12 deficiency A 19 year-old woman complains of two weeks of fatigue, fever and sore throat. She has a fever of 38.3°C, cervical lymphadenopathy and splenomegaly. The leukocyte count was 5,000/mm3 (80% lymphocytes, most of them atypical). Blood serum aspartate aminotransferase (AST) was 200 U/L. But serum bilirubin and alkaline phosphatase was normal (select one). A 15-year-old girl complains that she has been bruising easily for the last two weeks and has been feeling severe fatigue with pain in her back. She has widespread bruising, pallor, and tenderness over the vertebrae and both femurs. Hemoglobin concentration was 7.0 g/dL, the leukocyte count 2,000/mm3, and the number of platelets 15,000/mm3 (select one).